Many things can affect the way warfarin works. What happens if your warfarin is too high?Ī value higher than 3.5 increases the risk of bleeding problems. In order to shorten the response time for making a dosing change, patients are traditionally advised to have their INR test in the morning and to take their warfarin in the evening (so that the INR test result will be back in time to change that day’s warfarin dose if needed). Warfarin increases your risk of severe or fatal bleeding, especially if you have certain medical conditions, if you are 65 or older, or if you have had a stroke, or bleeding in your stomach or intestines. When should you not take warfarin?ĭo not take warfarin if you cannot take it on time every day. FFP requires blood group typing and thawing before use. What is the antidote of vitamin K?įresh frozen plasma (FFP) has been the mainstay for urgent anticoagulation reversal in patients taking vitamin K antagonists (eg, warfarin). While warfarin can be a lifesaver for patients suffering from atrial fibrillation and other conditions that may cause a fatal blood clot, the drug also has its drawbacks. Rare side effects include stroke, gangrene and death. The most common side effect - bleeding - can be life-threatening.
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